Induced pluripotent stem cells (iPS cells) are engineered stem cells, which exhibit properties very similar to embryonic stem cells (ES cells; Takahashi and Yamanaka, 2016).Both iPS cells and ES cells have an extraordinary self-renewal capacity and can differentiate into all cell types of our body, including hematopoietic stem/progenitor cells and
It is common in regression discontinuity analysis to control for read more third- or fifth-degree polynomials of the assignment variable.Such models can overfit, leading to causal inferences that are substantively implausible and that arbitrarily attribute variation to the high-degree polynomial or the discontinuity.This paper examines two recent s
Summary: Background: The diagnosis of chronic obstructive pulmonary disease (COPD) is based on spirometry that requires a forced expiratory manoeuvre, which is laborious and difficult for mass screening.Impulse oscillometry (IOS) is easier than spirometry and performed with tidal breathing.We sought to develop an equation for predicting forced expi
The Class I Major Histocompatibility Complex (MHC) is a central protein in immunology as it binds to intracellular peptides and displays them at the cell surface for recognition by T-cells.The structural analysis of bound peptide-MHC complexes (pMHCs) holds the promise of interpretable and general binding prediction (i.e., testing whether a given p